At the time we went for cruise ***Edited to remove commercial reference*** last year, we stored some ginger which provides immediate relief. If you look medicines, the best one will be scopolamine patches; it is worn behind the ear like a tiny band-aid. It is the most common prescription drug for seasickness. Scopolamine also comes in pill form. The patches last up to three days, provide time-release doses of the drug, and are usually very effective for preventing nausea.