Everyone reacts differently to medications. Some people will have no problems with scopalomine; others will have bad side effects. No one answer will help everyone.
I generally distrust medications that are delivered intradermally (through a patch) because you have no regulation of the dosage given. I have a friend who had stroke-like side effects from the scop patch - and another who had no problems at all.
For Barb - do check with your MD or pharmacist. My MD after reviewing the meds I take, suggested that if I was really that afraid of being seasick suggested taking a bonine at bedtime the night before I boarded the ship, and one at bedtime every night through the duration of the cruise. It worked like a charm for me - but then again that is me. For some people Bonine doesn't work.