If you are looking for a true "once in a lifetime" and money no object, then consider Cruise West, Lindblad etc. way superior for scenic sailing, knowledgable personal one on one attention, wildlife etc.
If looking at the major lines and cruise only (are you interested in 2 weeks with a week interior travel???) I think the best routing, with 2 glaciers and 3 ports are the HAL round trip Vancouver Glacier Bay trips. Just excellent itinerary, smaller ships, plenty of deck space etc.
But ANY Alaska cruise is a compromise, so look at ports, time in ports, glacier, routing, ship naturalist, price. Budget fully for costly excursions, you get only half a trip without them.