As stated, you can always request a room assignment to mid ship. I just returned from sailing on the Conquest for the second time and have cruised on the Holiday twice as well (also Sensation and Fantasy). The Conquest is such a large vessel that you do not have nearly as much movement as the Holiday.
I have always used the prescription patch while others in my party used dramamine. The patch worked fine, but I felt bad for a week after I stopped using it. I was lethargic and very dizzy. This time, I opted for the dramamine and did not even take it every day. I bought the less drowsy, 24 hour kind and never had a problem. Whatever you use, start it ahead of the trip.
Hope you have as much fun on the Conquest as we have had.