We were on the Jubliee to Hawaii a few years ago and my Dad and his wife were very seasick. They did take the Dramimine, except it wouldn't stay down. I bought them the wrist bands from the ships store and they worked wonderful. They were able to leave thier cabin to eat dinner after a whole day just laying in bed. I just saw these wrist bands in Target for about $8.00. They are well worth it. All they do is put a small amount of pressure on the inner wrist. They look like a wrist sweat band. There is no medication in them at all.