If you use Spybot freeware to scan for spyware, do not forget to immunize. My system is much cleaner since I started following the immunization procedure.... in fact, Spybot has not detected a threat since.
The "immunization" feature blocks malicious adware from infesting your PC, kinda like a doorman. You must also keep this feature up-to-date.
Before I began immunizing, there were always one or two "little buggers" hanging around after every scan that needed zapping.
Also run AdAware freeware. It sometimes detects things Spybot misses, and vice-versa. Neither will, as yet, clean out the self-preserving CoolWebSearch malware completely from your registry. If you have this highly malicious bug, seek very good help in removing it.
Just 1 month to go until the "Cruise Cynic Mystery Cruise" ... January 2008