About 1 mile separates the cruise terminal and airport in San Diego. You will have more than enough time. Keep it simple and take a taxi. Or, if you are like me and want to over-plan everything, use my favorite local shuttle service, Cloud 9 (http://www.cloud9shuttle.com). Worst case, you could walk along the waterfront, enjoy the beautiful day and the great weather here, even in November, and still make it on time.