It depends on what you are looking for. They Hyatt Regency Downtown is a closer and a better walk to Bayside Market, especially after dark. It is also closer to other shopping. It is about a dollar or two more for the cab ride to the port from the Hyatt and you will not have a view of the port from the Hyatt.
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"There is a great difference between being well traveled and just having been to many places." ~Me