Hotel Belvedere is a nice boutique hotel on 48th Street between 8th and 9th Avenue.
Their website is www.belvederehotelnyc.com
I stayed there in May after my Voyager cruise and found the hotel to be very nice and QUIET. It's on 48th Street closer to 8th Ave than 9th. But it's in a great area near Times Square and Central Park.
I stayed at the NY Hilton and Towers on 53rd and Broadway and the Waldorf Astoria last year, and in these hotels you heard a lot of outside noise. NYC is very noisy, sirens, trucks etc all night long. The Belvedere is on a side street and it was very quiet. Anytime I stay in NYC again, I will stay at the Belvedere.
The rooms were clean and quite large. They even have a mini fridge, sink, and microwave. There is a restaurant in the hotel, but I did not eat there.
On 47th Street there are many small restaurants and a many places to eat on 8th Avenue as well. The theater district in close by and if you are sightseeing the Grey Line Double-Decker bus and Waterway tour office is right down 8th Avenue.
This is a very centrally located hotel.
Hope this helps as an option.