I have heard tell of people doing pub crawls there..not sure how these get started though...I think the party hardy atmosphere is more obvious at night. Mallory Square,at sunset is a nice place to view the spectacular sun sinking into the horizon, and, if you see the green flash ...wowow! Lots of street performers too, but, sadly most ships, I believe, leave too early to participate
Trip, with her book & tea!
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The cruise lines are doing their own Pub Crawls too- don't know offhand if NCL offers one, but it's basically a walking tour of the pubs downtown, the Hogs Breath Saloon, Sloppy Joe's , Rick's - you get 5 drinks for the price of 4 and sometimes a T shirt..... you can find a lot online also, but they are mostly in the pm when the ships have departed. The Duval Crawl comes to mind... You can DIY just as easily...
I would take the Conch train tour of Key West, it is a narrated tour of downtown and then it tours around, and stops at places of interest for photo opportunities. Gives a great history of the place and drops you back off on Duval St.